Seattle Children's Provider News

A Comprehensive Approach to Cerebral Palsy

Seattle Children’s is one of the top treatment destinations in the country for children with cerebral palsy, a distinction made possible by the collaboration and expertise of surgeons and physicians.

Families of children with cerebral palsy seeking treatment at Seattle Children’s have access to a breadth of expertise unique to the Pacific Northwest.

The Cerebral Palsy Program includes a complete array of specialists. An orthopedic surgery team, which includes seven surgeons experienced in lower extremity, two surgeons experienced in upper extremity and four surgeons experienced in spine, performs single-event multilevel orthopedic surgery (SEMLS) along with a number of other procedures to address high tone and shortened muscles.

The program’s nationally and internationally recognized neurosurgeons have expertise in intrathecal baclofen pumps, selective dorsal rhizotomy (SDR) and hemispherectomy for children with intractable seizures. Read full post »

Groundbreaking Research at Seattle Children’s Improving Bone Tumor and Sarcoma Treatment

Research into tumor paint, glue embolization treatments and other fields of oncology care has allowed practitioners in the Bone Tumor and Sarcoma Clinic to provide unparalleled cancer care to children in the Pacific Northwest.

The Bone Tumor and Sarcoma Clinic is one of the first of its kind in the U.S. in which orthopedic surgeons and oncologists work side by side in the same program. The clinic’s expertise includes two surgeons with fellowship training in both pediatric orthopedics and musculoskeletal surgical oncology and a third with training in both pediatric and adult musculoskeletal oncology. Their interdisciplinary backgrounds and emphasis on collaborative care has resulted in one of the largest, most comprehensive bone and soft tissue programs in the country.

An emphasis on communication

At weekly bone tumor conferences, oncology, orthopedic and radiology teams review and discuss individual patient cases. An additional weekly clinic that includes a broader group of providers offers another opportunity for clinicians to maximize each child’s progress.

“Sarcoma requires team-based care,” says Dr. Suzanne Yandow, chief of Pediatric Orthopedics and Sports Medicine at Seattle Children’s and professor of orthopedic surgery at UW Medicine. “We have to have constant discussions about patients in group settings, and we have an entire team of oncologists, nurse practitioners with expertise in sarcoma care, social workers, and others who attend these weekly meetings.” Read full post »

Teduglutide and Transplants: Moving the Field of Pediatric Intestinal Rehabilitation Forward

The Intestinal Rehabilitation Program at Seattle Children’s, the only program of its kind in the Pacific Northwest, is dedicated to reducing transplantation rates through innovative research that improves intestinal failure management.

Seattle Children’s was one of the largest recruiters for the first 12-week trial evaluating the efficacy and safety of the investigational drug teduglutide for patients with long-term TPN dependence related to short bowel syndrome. Already approved for short bowel syndrome treatment in adults, teduglutide is designed to reduce the need for TPN.

“Teduglutide is the first drug to be introduced to the commercial market that has a sound theoretical basis, as well as supportive preclinical and adult clinical studies, to improve intestinal adaptation above and beyond what can be achieved with the best standard of care,” says Dr. Simon P. Horslen, director of the Intestinal Rehabilitation Program and medical director of Solid Organ Transplantation at Seattle Children’s, and professor of pediatrics with UW Medicine. “Anything that has the potential to wean a child from TPN or even reduce the amount of TPN they receive will improve quality of life.”

Results from the initial 12-week trial were promising. Among 42 children ages 1 to 17, the treatment was associated with overall reductions in TPN, in some cases as significant as 41%. Four children were weaned from TPN entirely during the study.

Horslen and his co-investigator, Dr. Danielle Wendel, gastroenterologist at Seattle Children’s and assistant professor at UW Medicine, are awaiting results from a recently completed 24-week study.

“Teduglutide is a huge step forward in the management of intestinal failure,” Horslen says. Read full post »

Uncovering the Genetic Roots of Pediatric Pancreatitis

Dr. Matthew Giefer’s pioneering research into the causes of early-onset pancreatitis has created new potential for diagnosing and treating the disorder in children.

Understanding the causes of pediatric pancreatitis – a condition many doctors may overlook when seeing children with abdominal issues – can lead to more timely and effective treatments.

It appears that genetics play a bigger role than previously thought, according to research conducted by Dr. Matthew Giefer, director of Gastrointestinal Endoscopy at Seattle Children’s and assistant professor at UW Medicine, and an international team of physicians involved in the INSPPIRE (International Study group of Pediatric Pancreatitis: In search for a cuRE) trial.

The team analyzed 342 children ages 0 to 18 diagnosed with either acute recurrent or chronic pancreatitis and found that family history and mutations on the PRSS1 or CTRC genes were the factors most strongly associated with early-onset pancreatitis. Surprisingly, 71% of children with this form of the disease had at least one gene mutation known to cause pancreatitis. Children with later onset pancreatitis, which generally develops after age 6, were less likely to have these genetic risk factors. Read full post »

Innovative Research Driving Change for Children With Hepatologic Challenges

At Seattle Children’s, the Pacific Northwest’s only dedicated pediatric hepatologists are actively engaged in research consortiums and working to improve treatments for pediatric liver diseases.

 Two of these physicians, Dr. Evelyn K. Hsu, program director of the Advanced/Transplant Hepatology Fellowship at UW Medicine and Seattle Children’s, and Dr. Karen F. Murray, chief of the Division of Gastroenterology and Hepatology at Seattle Children’s and vice chair of clinical affairs for the Department of Pediatrics at UW Medicine, have spearheaded a number of innovative studies that have improved children’s access to lifesaving transplants and medications. Read full post »

Upcoming CME Events

The following CME Events are being held this month:

On January 17, Dr. Kenneth Gow and Dr. Deepti Gupta will be presenting on “Vascular Anomalies – More Than Skin Deep” in Everett. For more information, please contact Physician Liaison Jen Mueller at Jen.Mueller@seattlechildrens.org.

On January 25, Dr. Kelly Pham will be presenting on “Ambulatory Cerebral Palsy” in the Tri-Cities. For more information, please contact Physician Liaison Kenton McAllister at Kenton.McAllister@seattlechildrens.org. Read full post »

New Medical Staff

Medical Providers

  • Amanda Allison, MD, Seattle Children’s, Emergency
  • Anne Coleman, MD, Allegro Pediatrics – Bellevue, Pediatrics
  • Jessica Jenness, PhD, Seattle Children’s, Psychology
  • Joy Kawamura, PhD, Seattle Children’s, Psychology
  • Tyler Ketterl, MD, Seattle Children’s, Hematology-Oncology
  • Aaron Lyon, PhD, Seattle Children’s, Psychology
  • Kyle Nagle, MD, MPH, Seattle Children’s, Orthopedics
  • Jay Sarthy, MD, PhD, Seattle Children’s, Hematology-Oncology
  • Alexia Spanos, PhD, DBT Center of Seattle, Psychology
  • Stephanie Srur, DO, Olympia Pediatrics, PLLC, Pediatrics
  • Mark Wainwright, MD, PhD, Seattle Children’s, Neurology

Allied Health Professionals

  • Hannah Cody, PA-C, Seattle Children’s, Neonatology
  • Wendy Fairall, ARNP, South Sound Pediatric Associates, Pediatrics
  • Laura Hopper, ARNP, Odessa Brown Children’s Clinic, Pediatrics
  • Nathaniel Johnson, ARNP, Seattle Children’s, Neonatology
  • Tacie Reger, ARNP, Seattle Children’s, Neonatology
  • Joseph Yanity, PA-C, Seattle Children’s, Neonatology

Read full post »

Identifying Fatty Liver Disease

A Q&A With Dr. Niviann Blondet

Nonalcoholic fatty liver disease (NAFLD) – the accumulation of fat in the liver – is the most common liver disorder in the United States, affecting approximately 10% of children. Although incidence is increasing, this condition is uniquely difficult to diagnose.

To address this issue, Seattle Children’s has opened a new Fatty Liver Clinic to treat patients with a multidisciplinary approach.

“We estimate about 10 million children have fatty liver disease, but there’s a large population that goes undiagnosed,” said Dr. Niviann Blondet, a gastroenterologist at Children’s. “It’s not until they develop cirrhosis that they seek medical attention.”

Dr. Blondet offers the following information to providers in hopes that patients might be diagnosed sooner and treated more effectively.

What are the risk factors of NAFLD?

Obesity is the most significant risk factor. There is a direct correlation between NAFLD and body mass index (BMI). However, the disease can occur in children within a normal weight range.

The prevalence of NAFLD increases throughout childhood, possibly because BMI increases with age in children.

Studies have also shown an association with insulin resistance. NAFLD increases the risk of developing type 2 diabetes and may worsen glycemic control in children with diabetes and contribute to the development and progression of chronic diabetic complications.

Gender can also be a contributing factor. NAFLD is approximately 40% more common in boys than girls. Read full post »

Upcoming CME Events in Tri-Cities, Everett

On December 7, 2017 Dr. Kathleen Kieran will be presenting on “Top 5 Questions I Get From PCP’s” in the Tri-Cities. For more information, please contact Physician Liaison, Kenton McAllister at Kenton.Mcallister@seattlechildrens.org

On December 12, 2017 Dr. Niviann Blondet will be presenting on “Non-Alcoholic Fatty Liver Disease” in Everett. For more information, please contact Physician Liaison, Jen Mueller at Jen.Mueller@seattlechildrens.org

 

New Medical Staff

Medical Providers

  • Alali Abdulaziz, MB BS, PhD, Harborview Medical Center, Neurosurgery
  • Dupuis Daniel, DDS, MSD, Northwest Pediatric Dentistry, Dentistry
  • McCabe Liana, MD, Virginia Mason University Village Medical Center, Pediatrics

Allied Health Professionals

  • Carl Anderson, ARNP, DNP, Seattle Children’s, Emergency Department
  • Susanna Fenstermacher, ARNP, Seattle Children’s, Emergency Department
  • Tera Johnson, ARNP, Seattle Children’s, Emergency Department
  • Michelle Murphy, ARNP, Seattle Cancer Care Alliance, Cancer and Blood Disorders Center
  • Misty Smith, ARNP, Seattle Children’s, Neonatology
  • Candy Yu, ARNP, Seattle Cancer Care Alliance, Cancer and Blood Disorders Center